66 Results for "

Prunus mume Siebold & Zucc.

" in MedChemExpress (MCE) Product Catalog:
Products (66)

66 Results for "Prunus mume Siebold & Zucc." in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-N0631
CAS No.: 131189-57-6
Cornuside is an iridoid glycoside with anti-allergic, anti-inflammatory, and neuroprotective activities. Cornuside exerts anti-allergic activity by downregulating the p38 MAPK, JNK, and NF-κB signaling pathways, and inhibits IgE-mediated histamine release from mast cells. Cornuside improves cognitive impairment in mice by inhibiting BACE1 activity (IC50 = 55.84 μg/mL) and enhancing ChAT activity. Cornuside inhibits LPS (HY-D1056)-induced inflammatory mediators, including iNOS, COX-2, PGE2, TNF-α, IL-6, and IL-1β, by suppressing NF-κB activation .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-N0263
CAS No.: 58812-37-6
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N5112B
CAS No.: 24502-79-2
Synonyms: Isoarnebin I
β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative that can be isolated from Lithospermum erythrorhizon Sieb. et Zucc. β,β-Dimethylacrylshikonin promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. β,β-Dimethylacrylshikonin inhibits Notch-1 activation. β,β-Dimethylacrylshikonin inhibtis tumor cell proliferation, induces tumor cell apoptosis, and inhibits tumor growth .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N2394
CAS No.: 38840-23-2
Emodin-1-O-β-D-glucopyranoside, isolated from medicinal plant Polygonum cuspidatum Sieb. & Zucc, is a potent and noncompetitive bacterial neuraminidase (BNA) inhibitor with an IC50 of 0.85 μM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N1391
CAS No.: 78432-77-6
Synonyms: 10-Deacetylpaclitaxel
10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N1547
CAS No.: 3443-28-5
Prudomestin, isolated from the heartwood of Prunus domestica, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6 µM) .
loading...
    loading...
Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
loading...
    loading...
Cat. No.: HY-N8903
CAS No.: 222973-44-6
Mumefural is a bioactive component of the processed fruit of Prunus mume Sieb. Mumefural inhibits platelet aggregation. Mumefural shows anti-thrombotic effects and ameliorates cognitive impairment .
loading...
    loading...
Cat. No.: HY-N6005
CAS No.: 3843-74-1
Methyl caffeate is a phenylpropanoid, antibacterial agent, and Apoptosis-inducing agent. Methyl caffeate can be isolated from the flowers of peach Prunus persica (L.). Methyl caffeate upregulates the expression of pro-apoptotic proteins Bid, Bax and p53, and downregulates the expression of anti-apoptotic protein BCL-2. Methyl caffeate downregulates SASP factors. Methyl caffeate enhances glucose-stimulated insulin secretion. Methyl caffeate inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, fungi, and Mycobacterium tuberculosis strains. Methyl caffeate can be used in studies related to breast cancer, type 2 diabetes, and tuberculosis .
loading...
    loading...
Cat. No.: HY-142026
CAS No.: 142449-89-6
Synonyms: (+)-Vitisin A
Vitisin A ((+)-Vitisin A) is an orally active natural product with multiple pharmacological activities including anti-inflammatory, anti-tumor, anti-oxidant, anti-pathogenic microorganism, hypoglycemic and lipid-regulating, anti-osteoporotic, neuroprotective and cardiovascular protective effects. Vitisin A exhibits inhibitory effects on human AChE and MAO-B with IC50 values of 1.29 µM and 4.94 µM, respectively. Vitisin A inhibits the ERK, MAPK, NF-κB, STAT1, HMGCR and TRAF6 pathways, downregulates the related phosphorylation and protein expression, while activates the Nrf2/HO-1 pathway and upregulates p21 expression. Vitisin A induces tumor cell apoptosis and cell cycle arrest, inhibits adipogenesis and lipid accumulation, while alleviates oxidative stress, suppresses inflammatory responses, blocks hepatic fibrosis, Cuproptosis and cholesterol synthesis, and increases the expression levels of central BDNF and TrkB. Vitisin A can be used in the research of tumors, infectious diseases, metabolic diseases, bone and joint diseases, liver diseases, skin injuries, as well as neurodegenerative and cognitive dysfunction-related diseases .
loading...
    loading...
Cat. No.: HY-N7683
CAS No.: 89595-66-4
Prunetin 5-O-β-D-glucopyranoside is an isoflavone. Prunetin 5-O-β-D-glucopyranoside can be isolated from the pedicels of Prunus avium and Prunus cerasus. Prunetin 5-O-β-D-glucopyranoside acts as a non-competitive α-glucosidase inhibitor, with a IC50 of 56.05 μg/mL and a Ki of 121 μg/mL against Saccharomyces cerevisiae α-glucosidase. Prunetin 5-O-β-D-glucopyranoside can be used in studies related to type 2 diabetes .
loading...
    loading...
Cat. No.: HY-N2247
CAS No.: 36531-08-5
Guaiacin is a arylnaphthalene type lignin isolated from the barks of Machilus thunbergii SIEB. et ZUCC (Lauraceae). Guaiacin significantly increases alkaline phosphatase activity and osteoblast differentiation .
loading...
    loading...
Cat. No.: HY-N1216
CAS No.: 126882-53-9
Ssioriside (compound 9) is a lignan xyloside, which can be isolated from the barks of Prunus ssiori and Prunus padus .
loading...
    loading...
Cat. No.: HY-N21140
Prunus mume polysaccharide is a polysaccharide derived from Prunus mume.
loading...
    loading...
Cat. No.: HY-N20969
Prunus mume fruit polysaccharide is a polysaccharide derived from Prunus mume fruit.
loading...
    loading...
Cat. No.: HY-N20820
Prunus mume extract is an extract isolated fromPrunus mume.
loading...
    loading...
Cat. No.: HY-W127616A
CAS No.: 915-05-9
Synonyms: Sitosteryl acetate, 95%
β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .
loading...
    loading...
Cat. No.: HY-N1742
CAS No.: 67214-05-5
Synonyms: 2''-O-p-Cumaroyleuglanin; Kaempferol 3-O-[2′′-(E)-p-coumaroyl]-α-L-arabinofuranoside
2''-O-Coumaroyljuglanin (2''-O-p-Cumaroyleuglanin) is a flavonoid which can be isolated from the flowers of Prunus spinosa .
loading...
    loading...
Cat. No.: HY-N12878
CAS No.: 20300-53-2
Calleryanin is a phenolic glycoside, which is mainly isolated from Maloideae and Prunus of the family Rosaceae. Calleryanin is used in study of plant defense mechanisms and new drugs development .
loading...
    loading...
Cat. No.: HY-N8956
CAS No.: 1253202-75-3
Pachysamine M (Compound 5) is a pregnane alkaloid. Pachysamine M is isolated from naturalPachysandra terminalisSieb. et Zucc .
loading...
    loading...